Clinically validate your product’s safety with our HRIPT service. Assess skin sensitization potential under dermatologist supervision for global regulatory compliance.
Human Repeat Insult Patch Test (HRIPT) – Assess Sensitization & Allergenicity
The Human Repeat Insult Patch Test (HRIPT) is a gold-standard clinical study used to evaluate whether a cosmetic, personal care, or topical pharmaceutical product causes skin sensitization or allergic reactions after repeated exposure. It is essential for products intended for frequent or long-term use.
Conducted under strict dermatologist supervision, the product is applied to the same area of skin over multiple cycles—followed by a rest and rechallenge phase—to detect any delayed hypersensitivity reactions. This test is critical for validating claims like “hypoallergenic,” “non-sensitizing,” and “safe for sensitive skin.”
HRIPT supports global regulatory requirements and assures consumers of the product’s long-term safety and tolerance.
Claims That Can Be Made Based on Human Repeat Insult Patch Test (HRIPT)
(When conducted under validated protocols like ISO 10993-10 or OECD 406, and dermatologist-supervised)
The HRIPT is a gold-standard clinical study used to assess a product’s potential to cause skin sensitization or allergic reactions over repeated exposure. If a product passes this test, the following claims can be made:
✅ Skin Sensitization & Allergy Safety Claims
✅ Product Tolerance Claims
✅ Regulatory & Scientific Claims
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